SHOKHEN, M. A. : rechercher sur Z-Library

Michael Shokhen, Amnon Albeck

Année:

1989

Fichier:

PDF, 79 KB

1989

Factors determining the relative stability of anionic tetrahedral complexes in serine protease catalysis and inhibition

Journal:

Anatoly M. Belostotskii, Michael Shokhen, Hugo E. Gottlieb, Alfred Hassner

Année:

2000

Langue:

english

Fichier:

PDF, 257 KB

english, 2000

Conformational Preferences for 3-Piperideines: An Ab Initio and Molecular Mechanics Study

Journal:

Chemistry - A European Journal

Année:

2001

Langue:

english

Fichier:

PDF, 205 KB

english, 2001

The Cooperative Effect Between Active Site Ionized Groups and Water Desolvation Controls the Alteration of Acid/Base Catalysis in Serine Proteases

Dr. Michael Shokhen, Tamar Traube, Dr. Subramaniam Vijayakumar, Michal Hirsch, Neta Uritsky, Dr. Amnon Albeck

Journal:

ChemBioChem

Année:

2007

Langue:

english

Fichier:

PDF, 370 KB

english, 2007

Differentiating Serine and Cysteine Protease Mechanisms by New Covalent QSAR Descriptors

Journal:

ChemBioChem

Année:

2011

Langue:

english

Fichier:

PDF, 239 KB

english, 2011

ChemInform Abstract: Conformational Preferences for 3-Piperideines: An ab initio and Molecular Mechanics Study.

Anatoly M. Belostotskii, Michael Shokhen, Hugo E. Gottlieb, Alfred Hassner

Journal:

Année:

2002

Fichier:

PDF, 23 KB

2002

Enzyme Isoselective Inhibitors: Application to Drug Design

Bioorganic & Medicinal Chemistry

Journal:

ChemMedChem

Année:

2006

Langue:

english

Fichier:

PDF, 126 KB

english, 2006

Enzyme Isoselective Inhibitors: A Tool for Binding-Trend Analysis

Rachel Ozeri, Netaly Khazanov, Nurit Perlman, Michael Shokhen, Amnon Albeck

Journal:

ChemMedChem

Année:

2006

Langue:

english

Fichier:

PDF, 150 KB

english, 2006

Peptidyl epoxides extended in the P′ direction as cysteine protease inhibitors: Effect on affinity and mechanism of inhibition

Nurit Perlman, Maya Hazan, Michael Shokhen, Amnon Albeck

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 515 KB

english, 2008

Semi-empirical mo study of reaction mechanism of carbinolamines formation by mindo/3 method

M.A. Shokhen, D.A. Tikhomirov, A.V. Yeremeyev

Journal:

Tetrahedron

Année:

1983

Langue:

english

Fichier:

PDF, 397 KB

english, 1983

Is there a weak H-bond → LBHB transition on tetrahedral complex formation in serine proteases?

Michael Shokhen, Amnon Albeck

Journal:

Michael Shokhen, Amnon Albeck

Année:

2004

Langue:

english

Fichier:

PDF, 218 KB

english, 2004

Identification of protons position in acid–base enzyme catalyzed reactions: The hepatitis C viral NS3 protease

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 343 KB

english, 2004

Screening of the active site from water by the incoming ligand triggers catalysis and inhibition in serine proteases

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 368 KB

english, 2008

Challenging a paradigm: Theoretical calculations of the protonation state of the Cys25-His159 catalytic diad in free papain

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 347 KB

english, 2009

The mechanism of papain inhibition by peptidyl aldehydes

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 485 KB

english, 2011

Chiroptical properties of the nonplanar amide chromophore in n-acylaziridines

G. V. Shustov, F. D. Polyak, G. K. Kadorkina, I. A. Vosekalna, M. A. Shokhen, R. K. Alekperov, A. V. Eremeev, R. G. Kostyanovskii

Journal:

D. A. Tikhomirov, M. A. Shokhen, A. V. Eremeev

Année:

1989

Langue:

english

Fichier:

PDF, 614 KB

english, 1989

Quantum-chemical study of the electrophilicities of ynamino and ynaziridino esters

Journal:

V. G. Andrianov, M. A. Shokhen, A. V. Eremeev

Année:

1989

Langue:

english

Fichier:

PDF, 337 KB

english, 1989

Dependence of the reactivity of five-membered heterocycles on their structure. 3. Proton affinity of azoles and oxazoles

Journal:

V. G. Andrianov, M. A. Shokhen, A. V. Eremeev

Année:

1989

Langue:

english

Fichier:

PDF, 249 KB

english, 1989

Dependence of the reactivity of five-membered aromatic heterocycles on their structure. 4. Proton affinity of N-aminoazoles

Journal:

V. G. Andrianov, M. A. Shokhen, A. V. Eremeev

Année:

1989

Langue:

english

Fichier:

PDF, 213 KB

english, 1989

Dependence of the reactivity of five-membered aromatic heterocycles on their structure. 5. Protonation of furazane, furoxane, and their aminoderivatives

Journal:

Robert Glaser, Vitaly Khutorsky, Michael Shokhen

Année:

1989

Langue:

english

Fichier:

PDF, 337 KB

english, 1989

Scopolamine and atropineN-methyl diastereomer stability.Ab initiocalculations onO-formylscopine andO-formyltropine model compounds

Journal:

Structural Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 830 KB

english, 1997

The Source for the Difference Between Sulfhydryl and Hydroxyl Anions in Their Nucleophilic Addition Reaction to a Carbonyl Group: A DFT Approach.

Michael Shokhen, Dorit Arad

Journal:

Journal of Molecular Modeling

Année:

1996

Langue:

english

Fichier:

PDF, 122 KB

english, 1996

Anionic Tetrahedral Complexes as Serine Protease Inhibitors

Michael Shokhen, Dorit Arad

Journal:

Journal of Molecular Modeling

Année:

1996

Langue:

english

Fichier:

PDF, 104 KB

english, 1996

Evaluation of the contribution of intramolecular interactions to proton affinity of aminofurazans by the SCF-MO method in the mindo/3 approximation

M. A. Shokhen, V. G. Andrianov, A. V. Eremeev

Journal:

V. G. Andrianov, M. A. Shokhen, A. V. Eremeev, S. V. Barmina

Année:

1979

Langue:

english

Fichier:

PDF, 225 KB

english, 1979

Dependence of the reactivity of five-membered aromatic heterocycles on their structure. 1. Effect of the number, type, and position of nitrogen atoms on the proton affinity of aminoazoles

Journal:

V. G. Andrianov, M. A. Shokhen, A. V. Eremeev, S. V. Barmina

Année:

1987

Langue:

english

Fichier:

PDF, 415 KB

english, 1987

Effect of substituents on the relative stability of furoxan isomers

Journal:

M. A. Shokhen, V. G. Andrianov, A. V. Eremeev, S. V. Barmina

Année:

1986

Langue:

english

Fichier:

PDF, 310 KB

english, 1986

Dependence of the reactivity of five-membered aromatic heterocycles on their structure. 2. Effect of aza substitution on the proton affinity of aminofurans

Journal:

M. A. Shokhen, A. V. Eremeev, R. G. Kostyanovskii

Année:

1987

Langue:

english

Fichier:

PDF, 316 KB

english, 1987

Analysis of the effect of the number of α-oxygen and α-fluorine atoms on the nucleophilicity of amines relative to a carbonyl substrate

Journal:

Russian Chemical Bulletin

Année:

1985

Langue:

english

Fichier:

PDF, 389 KB

english, 1985

Asymmetric nitrogen 60. Acylation as a pathway to optically active 1,3,3-trisubstituted diaziridines

G. V. Shustov, S. N. Denisenko, M. A. Shokhen, R. G. Kostyanovskii

Journal:

Russian Chemical Bulletin

Année:

1988

Langue:

english

Fichier:

PDF, 558 KB

english, 1988

Dependence of the inversion barrier of the aziridine nitrogen atom on the HCH angles

M. A. Shokhen, A. V. Eremeev, R. G. Kostyanovskii

Journal:

Russian Chemical Bulletin

Année:

1988

Langue:

english

Fichier:

PDF, 71 KB

english, 1988

The Catalytic Machinery of Rhomboid Proteases: Combined MD and QM Simulations

Uritsky, Neta, Shokhen, Michael, Albeck, Amnon

Journal:

Journal of Chemical Theory and Computation

Année:

2012

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2012

Calendar

Traube, Tamar, Shokhen, Michael, Albeck, Amnon

Journal:

Atmospheric Environment

Année:

1994

Langue:

english

Fichier:

PDF, 110 KB

english, 1994

A new method for filtering of reactive “warheads” of transition-state analog protease inhibitors

Traube, Tamar, Shokhen, Michael, Albeck, Amnon

Journal:

European Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2014

From Catalytic Mechanism to Rational Design of Reversible Covalent Inhibitors of Serine and Cysteine Hydrolases

Shokhen, Michael, Hirsch, Michal, Khazanov, Netaly, Ozeri, Rachel, Perlman, Nurit, Traube, Tamar, Vijayakumar, Subramaniam, Albeck, Amnon

Journal:

Israel Journal of Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 3.10 MB

english, 2014

EMBM − A New Enzyme Mechanism-Based Method for Rational Design of Chemical Sites of Covalent Inhibitors

Traube, Tamar, Vijayakumar, Subramaniam, Hirsch, Michal, Uritsky, Neta, Shokhen, Michael, Albeck, Amnon

Journal:

Journal of Chemical Information and Modeling

Année:

2010

Langue:

english

Fichier:

PDF, 575 KB

english, 2010

Nitrogen Inversion in Cyclic Amines and the Bicyclic Effect

Belostotskii, Anatoly M., Gottlieb, Hugo E., Shokhen, Michael

Journal:

Journal of Organic Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 214 KB

english, 2002

Structural and mechanistic aspects of 3C proteases from the picornavirus family

Arad, Dorit, Kreisberg, Racheli, Shokhen, Michael

Journal:

Journal of Chemical Information and Modeling

Année:

1993

Langue:

english

Fichier:

PDF, 1.23 MB

english, 1993

Application of EMBM to Structure-Based Design of Warheads for Protease Inhibitors

Traube, Tamar, Shokhen, Michael, Albeck, Amnon

Journal:

Molecular Informatics

Année:

2014

Langue:

english

Fichier:

PDF, 952 KB

english, 2014

ChemInform Abstract: Asymmetric Nitrogen. Part 64. Chiroptical Properties of a Nonplanar Amide Chromophore in N-Acylaziridines.

SHUSTOV, G. V., POLYAK, F. D., KADORKINA, G. K., VOSEKALNA, I. A., SHOKHEN, M. A., ALEKPEROV, R. K., EREMEEV, A. V., KOSTYANOVSKII, R. G.

Journal:

Uritsky, Neta, Shokhen, Michael, Albeck, Amnon

Année:

1989

Fichier:

PDF, 93 KB

1989

Stepwise Versus Concerted Mechanisms in General-Base Catalysis by Serine Proteases

Journal:

Angewandte Chemie

Année:

2016

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2016

ChemInform Abstract: Structure-Reactivity Relationship of Five-Membered Aromatic Heterocycles. Part 1. Influence of Number, Type, and Position of the Heteroatoms on the Proton Affinity of Aminoazoles.

ANDRIANOV, V. G., SHOKHEN, M. A., EREMEEV, A. V., BARMINA, S. V.

Journal:

ANDRIANOV, V. G., SHOKHEN, M. A., EREMEEV, A. V.

Année:

1987

Fichier:

PDF, 90 KB

1987

ChemInform Abstract: Dependence of the Reactivity of Five-Membered Aromatic Heterocycles on Their Structure. Part 5. Protonation of Furazan, Furoxan, and Their Amino Derivatives.

Journal:

SHOKHEN, M. A., ANDRIANOV, V. G., EREMEEV, A. V., BARMINA, S. V.

Année:

1990

Fichier:

PDF, 82 KB

1990

ChemInform Abstract: Structure-Reactivity Relationship of Five-Membered Aromatic Heterocycles. Part 2. Influence of Azasubstitution on the Proton Affinity of Aminofurans.

Journal: